Dr. Shai Efrati is a professor at Sackler School of Medicine and the Sagol School of Neuroscience of Tel Aviv University and the director of the Sagol Center for hyperbaric medicine and research at Shamir (Assaf-Harofeh) Medical Center in Israel. The center, under Prof. Efrati's management, has become one of the largest hyperbaric centers worldwide, currently treating more than 300 patients per day. Prof. Efrati is also the director of Research & Development at the Medical center, affiliated to Tel-Aviv University. Taking the two passions/positions together Dr. Efrati has initiated a research program focusing on neuroplasticity (regeneration of damaged brain tissue) by the use of Hyperbaric Oxygen Therapy (HBOT). In the first clinical studies, it was demonstrated that HBOT can induce neuroplasticity in post-stroke and Traumatic Brain Injury even years after the acute Insult. The important clinical results gained from the research program have led to fruitful ongoing cooperation including multidiscipline team focusing on the regenerative effects of hyperbaric oxygen in different types of brain injuries including TBI, Stroke, age-related cognitive/functional decline and Alzheimer disease, central sensitization syndrome (ex. Fibromyalgia) and PTSD.