Zhen Xu is Professor of Biomedical Engineering at the University of Michigan, Ann Arbor, MI. Her research focuses on ultrasound therapy and imaging. She is an international pioneer and leader of histotripsy, a non-invasive ultrasound therapy based on cavitation. She received the IEEE Ultrasonics, Ferroelectrics, and Frequency Control (UFFC) Outstanding Paper Award in 2006, The Federic Lizzi Early Career Award from The International Society of Therapeutic Ultrasound (ISTU) in 2015, the Fellow of American Institute of Medicine and Bioengineering in 2019, and The Lockhart Memorial Prize for Cancer Research in 2020. She is an associate editor for IEEE Transactions on UFFC and Frontiers in Biomedical Engineering, VP of IEEE Ultrasonics, and an elected board member of ISTU. She is a principal investigator of grants funded by National Institute of Health (NIH), Office of Navy Research, American Cancer Association, and Focused Ultrasound Foundation. She is also co-founder of HistoSonics, a startup company to commercially translating histotripsy for clinical applications.