The COVID-19 pandemic has intensified the need for accurate, trusted, public information about science and health. Swirling amid the global public health crisis is an "infodemic" - too much rapidly spreading information, especially disinformation and misinformation—fueling mistrust and, in some cases, endangering health and well-being in the US and around the world. This session will explore the challenges of communicating science and health findings, lessons learned from the pandemic, and strategies for making reliable science and health information trusted, accessible, understandable, and purposeful.