In the last decade, FasterCures and many stakeholders across the biomedical research ecosystem have driven initiatives to ensure that patients’ perspectives and input are appropriately represented across the product-development continuum and post-approval phase. FasterCures embarked on a series of activities to gather information about current advances in patient engagement and opportunities for action to drive meaningful progress. This report summarizes our assessment of the science of patient input, including areas that have seen the greatest progress, opportunities for action to accelerate the inclusion of patients’ perspectives in research, and the next steps for stakeholder action.